High resolution 3D imaging of liver subcellular architecture and its link to metabolic function

Gunes Parlakgul*, Ana Paula Arruda*, Song Pang, Erika Cagampan, Nina Min, Ekin Guney, Yankun Lee, Karen Inouye, Harald F. Hess, C. Shan Xu, Gokhan S Hotamisligil

Contact: 
gparlakg@hsph.harvard.edu
ghotamis@hsph.harvard.edu

Raw FIBSEM images are not compressed and can be viewed online. 
Segmentation images are compressed (.zip) and need to be downloaded, unzipped (decompressed) and then viewed. 
The total decompressed data size is 17 Terabytes. Compressed version of the data is around 2 Terabytes.

6461 is Lean liver
There are 5638 consecutive raw FIBSEM images 
and 5638 corresponding images in each segmentation class 
(ER, ER sheets, ER Tubules, Mitochondria, Lipid Droplet, Cell Membrane, Nuclear membrane) 

6464 is Obese1 liver
There are 7896 consecutive raw FIBSEM images 
and 7896 corresponding images in each segmentation class 
(ER, ER sheets, ER Tubules, Mitochondria, Lipid Droplet, Cell Membrane, Nuclear membrane)

9430 is Obese2 liver
There are 8501 consecutive raw FIBSEM images 
and 8501 corresponding images in each segmentation class 
(ER, ER sheets, ER Tubules, Mitochondria, Lipid Droplet, Cell Membrane, Nuclear membrane)

1857 is Obese Climp-63 overexpression liver
There are 3629 consecutive raw FIBSEM images 
and 3629 corresponding images in each segmentation class 
(ER, ER sheets, ER Tubules, Mitochondria, Lipid Droplet, Cell Membrane)