REL
2020-02-12
2020-07-15
2020-07-15
CryoEM reconstruction of human ABCG2 transporter with inhibitor MZ29 and 5D3-Fab
0000-0002-8207-2889
Kaspar
P
Locher
ETH Zurich
Otto-Stern-Weg 5
Zurich
ZH
Switzerland
8093
0000-0002-8207-2889
Kaspar
P
Locher
ETH Zurich
Otto-Stern-Weg 5
Zurich
ZH
Switzerland
8093
Jackson SM
Manolaridis I
Kowal J
Zechner M
Taylor NMI
Bause M
Bauer S
Bartholomaeus R
Bernhardt G
Koenig B
Buschauer A
Stahlberg H
Altmann KH
Locher KP
5.6
10.6019/EMPIAR-10374
EMDB
EMD-3953
Jackson SM
Manolaridis I
Kowal J
Zechner M
Taylor NMI
Bause M
Bauer S
Bartholomaeus R
Bernhardt G
Koenig B
Buschauer A
Stahlberg H
Altmann KH
Locher KP
Structural basis of small-molecule inhibition of human multidrug transporter ABCG2
Nature structural & molecular biology
Nat. Struct. Mol. Biol.
4
25
333
340
2018
English
10.1038/s41594-018-0049-1
29610494
Raw movies (mrc) without alignment with provided gain references, particles and final 3D refinement files with masks
Unaligned super-resolution multi-frame micrographs of MZ-29 inhibitor bound ABCG2-Fab.
/data/Movies
micrographs - multiframe
MRC
MRC
4094
50
1
50
4 BIT INTEGER
7676
0.42
7420
0.42
Unaligned super-resolution (K2 camera) multi-frame micrographs of MZ-29 inhibitor bound ABCG2-Fab. One movie is made of 50 frames (10sec in total/0.2s per frame, frame dose is 2.0 e/A2).
Extracted particles and corresponding star file
/data/Extracted_particles
picked particles - single frame - processed
MRCS
MRCS
587743
1
32 BIT FLOAT
384
0.84
384
0.84
All particles picked up with Gautomatch and extracted from all micrographs.