<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-11318" schemaVersion="0.63" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2022-11-11</depositionDate>
            <releaseDate>2023-11-07</releaseDate>
            <updateDate>2023-11-07</updateDate>
        </keyDates>
        <title>Tau filaments from the cellular fraction of Alzheimer's disease patient brain</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0002-8176-2618</authorORCID>
            <firstName>Benjamin</firstName>
            <lastName>Ryskeldi-Falcon</lastName>
            <organization type="academic">MRC Laboratory of Molecular Biology</organization>
            <townOrCity>Cambridge</townOrCity>
            <country>United Kingdom</country>
            <postOrZipCode>CB2 0QH</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0002-8176-2618</authorORCID>
            <firstName>Benjamin</firstName>
            <lastName>Ryskeldi-Falcon</lastName>
            <organization type="academic">MRC Laboratory of Molecular Biology</organization>
            <townOrCity>Cambridge</townOrCity>
            <country>United Kingdom</country>
            <postOrZipCode>CB2 0QH</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0002-8176-2618">Ryskeldi-Falcon BR-F</author>
            <author authorORCID="0000-0001-8832-8411">Behr TSB</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody></fundingBody>
                <code></code>
                <country></country>
            </grantReference>
        </grantSupport>
        <datasetSize units="TB">1.9</datasetSize>
        <entryDOI>10.6019/EMPIAR-11318</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-16039</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="true">
                    <author order="1">Fowler SL</author>
                    <author order="2">Behr TS</author>
                    <author order="3">Turkes E</author>
                    <author order="4">Cauhy PM</author>
                    <author order="5">Foiani MS</author>
                    <author order="6">Schaler A</author>
                    <author order="7">Crowley G</author>
                    <author order="8">Bez S</author>
                    <author order="9">Ficulle E</author>
                    <author order="10">Tsefou E</author>
                    <author order="11">O’Brien DP</author>
                    <author order="12">Fischer R</author>
                    <author order="13">Geary B</author>
                    <author order="14">Gaur P</author>
                    <author order="15">Miller C</author>
                    <author order="16">D’Acunzo P</author>
                    <author order="17">Levy E</author>
                    <author order="18">Duff KE</author>
                    <author order="19">Ryskeldi-Falcon B</author>
                    <title>Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease</title>
                    <journal>bioRxiv</journal>
                    <journalAbbreviation></journalAbbreviation>
                    <country></country>
                    <year>2023</year>
                    <externalReferences type="doi">10.1101/2023.04.30.537820</externalReferences>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Unaligned multiframe movies</name>
        <directory>/data/EMPIAR_Cell</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>12117</numImagesOrTiltSeries>
        <framesPerImage>40</framesPerImage>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>5760</imageWidth>
            <pixelWidth>0.834</pixelWidth>
            <imageHeight>4092</imageHeight>
            <pixelHeight>0.834</pixelHeight>
        </dimensions>
        <details>The files were written as gain-unnormalised integer MRC files by EPU and then converted to TIFF files by mrc2tif in the IMOD suite. During this process, the pixel size in the header was lost. The real pixel size is 0.834 Å/px. The dose rate is 0.89 e/Å2/frame. The files were collected in two sessions, with separate gain references. Please use the corresponding gain.tiff files a gain reference without any rotation or flipping.</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
