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        <keyDates>
            <depositionDate>2023-01-30</depositionDate>
            <releaseDate>2023-02-08</releaseDate>
            <updateDate>2023-02-08</updateDate>
        </keyDates>
        <title>PKA-phosphorylated CPVT variant human ryanodine receptor type 2 R2474S in the presence of calmodulin - RyR2-R2474S + CaM</title>
        <correspondingAuthor>
            <authorORCID>0000-0001-8851-4863</authorORCID>
            <firstName>Marco</firstName>
            <middleName>Cesar</middleName>
            <lastName>Miotto</lastName>
            <organization type="academic">Columbia University</organization>
            <street>1150 St Nicholas Ave</street>
            <townOrCity>New York</townOrCity>
            <stateOrProvince>New York</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>10032</postOrZipCode>
        </correspondingAuthor>
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            <authorORCID>0000-0001-8851-4863</authorORCID>
            <firstName>Marco</firstName>
            <middleName>Cesar</middleName>
            <lastName>Miotto</lastName>
            <organization type="academic">Columbia University</organization>
            <street>1150 St Nicholas Ave</street>
            <townOrCity>New York</townOrCity>
            <stateOrProvince>New York</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>10032</postOrZipCode>
        </principalInvestigator>
        <principalInvestigator>
            <authorORCID>0000-0002-8057-1502</authorORCID>
            <firstName>Andrew</firstName>
            <lastName>Marks</lastName>
            <organization type="academic">Columbia University</organization>
            <street>1150 St Nicholas Ave</street>
            <townOrCity>New York</townOrCity>
            <stateOrProvince>New York</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>10032</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0001-8851-4863">Miotto MC</author>
            <author>Weninger G</author>
            <author>Dridi H</author>
            <author>Yuan Q</author>
            <author>Liu Y</author>
            <author>Wronska A</author>
            <author>Melville Z</author>
            <author>Sittenfeld L</author>
            <author>Reiken S</author>
            <author authorORCID="0000-0002-8057-1502">Marks AR</author>
        </authorsList>
        <grantSupport>
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                <code></code>
                <country></country>
            </grantReference>
        </grantSupport>
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        <entryDOI>10.6019/EMPIAR-11403</entryDOI>
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        <scale>molecule</scale>
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    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-26413</emdbEntry>
            <emdbEntry>EMD-26414</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0001-8851-4863" order="1">Miotto MC</author>
                    <author order="2">Weninger G</author>
                    <author authorORCID="0000-0001-9533-7367" order="3">Dridi H</author>
                    <author order="4">Yuan Q</author>
                    <author authorORCID="0000-0002-8343-4431" order="5">Liu Y</author>
                    <author authorORCID="0000-0003-2288-2596" order="6">Wronska A</author>
                    <author authorORCID="0000-0001-8962-2612" order="7">Melville Z</author>
                    <author order="8">Sittenfeld L</author>
                    <author authorORCID="0000-0002-5807-3574" order="9">Reiken S</author>
                    <author authorORCID="0000-0002-8057-1502" order="10">Marks AR</author>
                    <title>Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment</title>
                    <journal>Science advances</journal>
                    <journalAbbreviation>Sci Adv</journalAbbreviation>
                    <country></country>
                    <issue>29</issue>
                    <volume>8</volume>
                    <year>2022</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1126/sciadv.abo1272</externalReferences>
                    <externalReferences type="pubmed">35857850</externalReferences>
                    <details>Raw movies</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>PKA-phosphorylated CPVT variant human ryanodine receptor type 2 R2474S in the presence of calmodulin - RyR2-R2474S + CaM</name>
        <directory>/data</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>12685</numImagesOrTiltSeries>
        <framesPerImage>50</framesPerImage>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>5760</imageWidth>
            <pixelWidth>0.83</pixelWidth>
            <imageHeight>4092</imageHeight>
            <pixelHeight>0.83</pixelHeight>
        </dimensions>
        <details>Reference: references/21aug04b_04142229_01_4092x5760_norm_0.mrc (must invert in Y).</details>
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        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
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