REL 2022-09-24 2025-10-28 2025-10-28 Molecular mechanism of Trypanosoma brucei Aquaporin 2 with Glycerol 0000-0002-7965-0895 Simone Nicole Weyand Department of Biochemistry, University of Cambridge 80 Tennis Court Road Cambridge Cambridgeshire United Kingdom CB21GA 0000-0002-7965-0895 Simone Nicole Weyand Department of Biochemistry, University of Cambridge 80 Tennis Court Road Cambridge Cambridgeshire United Kingdom CB21GA Weyand SN Gragera M 6.8 10.6019/EMPIAR-11410 EMDB molecule EMD-16864 Matusevicius M Corey RA Gragera M Yamashita K Sprenger T Ungogo MA Blaza JM Castro-Hartmann P Chirgadze DY Vedithi SC Afanasyev P Melero R Warshamanage R Gusach A Carazo JM Carrington M Blundell TM Murshudov G Stansfeld P Sansom M De Koning HP Tate CG Weyand SN Insights from aquaporin structures into drug-resistant sleeping sickness eLife 14 RP107460 2025 10.7554/eLife.107460.1 Aligned micrographs of Aqp2 from Trypanosoma brucei with glycerol (MotionCorr2 output) /data micrographs - single frame MRC MRC 2882 1 32 BIT FLOAT 4096 1.07 4096 1.07
Aligned (all frames) and dose-weighted micrographs from MotionCorr2.
data/*_aqp2_*_aligned_mic_DW.mrc Particle set of the final 3D reconstruction of Aqp2 + glycerol from Trypanosoma brucei /data/Export picked particles - single frame - processed MRCS MRCS 100075 1 32 BIT FLOAT 320 1.07 320 1.07
Particles from final 3D reconstruction.
data/Export/particles_007029.star data/Export/Particles Aligned micrographs of Aqp2 from Trypanosoma brucei with glycerol (MotionCorr2 output) /data micrographs - multiframe MRCS MRCS 2881 75 SIGNED 16 BIT INTEGER 4096 1.07 4096 1.07
data/*.mrcs