<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-11429" schemaVersion="0.63" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2023-02-06</depositionDate>
            <releaseDate>2023-08-18</releaseDate>
            <updateDate>2023-08-18</updateDate>
        </keyDates>
        <title>Structure of TDP-43 amyloid filaments from type A FTLD-TDP (individual 3)</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0002-8176-2618</authorORCID>
            <firstName>Benjamin</firstName>
            <lastName>Ryskeldi-Falcon</lastName>
            <organization type="academic">MRC Laboratory of Molecular Biology</organization>
            <townOrCity>Cambridge</townOrCity>
            <country>United Kingdom</country>
            <postOrZipCode>CB2 0QH</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0002-8176-2618</authorORCID>
            <firstName>Benjamin</firstName>
            <lastName>Ryskeldi-Falcon</lastName>
            <organization type="academic">MRC Laboratory of Molecular Biology</organization>
            <townOrCity>Cambridge</townOrCity>
            <country>United Kingdom</country>
            <postOrZipCode>CB2 0QH</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0001-7585-288X">Arseni D</author>
            <author authorORCID="0000-0002-8176-2618">Ryskeldi-Falcon B</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody>Medical Research Council (MRC, United Kingdom)</fundingBody>
                <code>MC_UP_1201/25</code>
                <country>United Kingdom</country>
            </grantReference>
        </grantSupport>
        <datasetSize units="TB">5.7</datasetSize>
        <entryDOI>10.6019/EMPIAR-11429</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-16628</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0001-7585-288X" order="1">Arseni D</author>
                    <author order="2">Chen R</author>
                    <author order="3">Murzin AG</author>
                    <author authorORCID="0000-0002-7602-6384" order="4">Peak-Chew SY</author>
                    <author authorORCID="0000-0002-1899-7676" order="5">Garringer HJ</author>
                    <author order="6">Newell KL</author>
                    <author authorORCID="0000-0001-9125-7001" order="7">Kametani F</author>
                    <author authorORCID="0000-0003-2208-7728" order="8">Robinson AC</author>
                    <author order="9">Vidal R</author>
                    <author authorORCID="0000-0002-1842-8019" order="10">Ghetti B</author>
                    <author authorORCID="0000-0001-7415-8159" order="11">Hasegawa M</author>
                    <author authorORCID="0000-0002-8176-2618" order="12">Ryskeldi-Falcon B</author>
                    <title>TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP</title>
                    <journal>Nature</journal>
                    <journalAbbreviation>Nature</journalAbbreviation>
                    <country></country>
                    <year>2023</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1038/s41586-023-06405-w</externalReferences>
                    <externalReferences type="pubmed">37532939</externalReferences>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Unaligned multiframe movies</name>
        <directory>/data/Movies</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>36507</numImagesOrTiltSeries>
        <framesPerImage>40</framesPerImage>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>5760</imageWidth>
            <pixelWidth>0.86</pixelWidth>
            <imageHeight>4092</imageHeight>
            <pixelHeight>0.86</pixelHeight>
        </dimensions>
        <details>The files were written as gain un-normalised integer MRC files by EPU and then converted to TIFF files by mrc2tif in the IMOD suite. During this process, the pixel size in the header was lost. The real pixel size is 0.86 Å/px. The dose rate is 0.75 e/Å2/frame. Please use the gain.tiff file a gain reference without any rotation or flipping.</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern>data/ManualPick</pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
