REL 2024-06-28 2025-02-03 2025-02-03 Cryo-EM structures of human vitamin C transporter SVCT1 0000-0002-6186-6647 Tsukasa Kusakizako Department of Biological Sciences, Graduate School of Science, The University of Tokyo 7-3-1, Hongo Bunkyo Tokyo Japan 113-0033 0000-0003-1813-7008 Osamu Nureki Department of Biological Sciences, Graduate School of Science, The University of Tokyo 7-3-1, Hongo Bunkyo Tokyo Japan 113-0033 Kobayashi TA Shimada H Sano FK Itoh Y Enoki S Okada Y Kusakizako T Nureki O 2.9 10.6019/EMPIAR-12159 EMDB molecule EMD-36201 EMD-36204 EMD-36205 EMD-36206 Kobayashi TA Shimada H Sano FK Itoh Y Enoki S Okada Y Kusakizako T Nureki O Dimeric transport mechanism of human vitamin C transporter SVCT1 Nature Communications Nat. Commun. 2024 English 10.1038/s41467-024-49899-2 N/A Unaligned multi-frame micrographs of human SVCT1 in the substrate-bound inward-open state /data/Dataset0 micrographs - multiframe TIFF TIFF 3753 48 1 48 UNSIGNED BYTE 5760 0.83 4092 0.83
HT: 300 kV Cs: 2.7 mm Flux: 50 e/A2 over 48 frames
data/Dataset0/*.tif Unaligned multi-frame micrographs of human SVCT1 in the substrate-free inward-open state /data/Dataset1 micrographs - multiframe TIFF TIFF 3474 48 1 48 UNSIGNED BYTE 5760 0.83 4092 0.83
HT: 300 kV Cs: 2.7 mm Flux: 50 e/A2 over 48 frames
data/Dataset1/*.tif Unaligned multi-frame micrographs of human SVCT1 in the intermediate and substrate-free occluded states /data/Dataset2 micrographs - multiframe TIFF TIFF 5907 48 1 48 UNSIGNED BYTE 5760 0.83 4092 0.83
HT: 300 kV Cs: 2.7 mm Flux: 50 e/A2 over 48 frames
data/Dataset2/*fractions.tiff