<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-12491" schemaVersion="0.65" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2024-12-12</depositionDate>
            <releaseDate>2025-07-23</releaseDate>
            <updateDate>2025-07-23</updateDate>
        </keyDates>
        <title>Cryo electron microscopy structure of human TRPM4 in SMA nanodisc</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0002-0928-4682</authorORCID>
            <firstName>Babatunde</firstName>
            <middleName>Edukpe</middleName>
            <lastName>Ekundayo</lastName>
            <organization type="academic">EPFL</organization>
            <street>Rte de la Sorge</street>
            <townOrCity>Lausanne</townOrCity>
            <stateOrProvince>vaud</stateOrProvince>
            <country>Switzerland</country>
            <postOrZipCode>1015</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0002-1185-4592</authorORCID>
            <firstName>Henning</firstName>
            <lastName>Stahlberg</lastName>
            <organization type="academic">EPFL</organization>
            <street>Rte de la Sorge</street>
            <townOrCity>Lausanne</townOrCity>
            <stateOrProvince>Vaud</stateOrProvince>
            <country>Switzerland</country>
            <postOrZipCode>1015</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0002-0928-4682">Ekundayo BE</author>
            <author authorORCID="0000-0002-3193-6077">Ni D</author>
            <author authorORCID="0000-0002-1185-4592">Stahlberg H</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody></fundingBody>
                <code></code>
                <country></country>
            </grantReference>
        </grantSupport>
        <datasetSize units="GB">449.9</datasetSize>
        <entryDOI>10.6019/EMPIAR-12491</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-19057</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="true">
                    <author authorORCID="0000-0002-0928-4682" order="1">Ekundayo B</author>
                    <author order="2">Arullampalam P</author>
                    <author authorORCID="0000-0002-5517-4951" order="3">Gerber CE</author>
                    <author order="4">Hämmerli A</author>
                    <author order="5">Guichard S</author>
                    <author order="6">Boukenna M</author>
                    <author authorORCID="0000-0003-1367-0671" order="7">Ross-Kaschitza D</author>
                    <author authorORCID="0000-0003-4930-1886" order="8">Lochner M</author>
                    <author authorORCID="0000-0002-8710-0260" order="9">Rougier J</author>
                    <author authorORCID="0000-0002-1185-4592" order="10">Stahlberg H</author>
                    <author authorORCID="0000-0003-0465-5138" order="11">Abriel H</author>
                    <author authorORCID="0000-0002-3193-6077" order="12">Ni D</author>
                    <title>Identification of a Binding Site for Small Molecule Inhibitors Targeting Human TRPM4</title>
                    <journal>bioRxiv</journal>
                    <journalAbbreviation></journalAbbreviation>
                    <country></country>
                    <language>English</language>
                    <externalReferences type="doi">10.1101/2024.01.22.576650</externalReferences>
                    <details>Doseweighted micrographs in mrc file format- Trpm4 bound to NBA</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Doseweighted micrographs in mrc file format- Trpm4 bound to NBA</name>
        <directory>/data</directory>
        <category>micrographs - single frame</category>
        <headerFormat>MRC</headerFormat>
        <dataFormat>MRC</dataFormat>
        <numImagesOrTiltSeries>7199</numImagesOrTiltSeries>
        <framesPerImage>1</framesPerImage>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>4096</imageWidth>
            <pixelWidth>0.726</pixelWidth>
            <imageHeight>4096</imageHeight>
            <pixelHeight>0.726</pixelHeight>
        </dimensions>
        <details></details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
