REL
2025-04-10
2025-10-09
2025-10-09
Single particle Cryo EM of the C-terminal half LRRK2 bound to MLi-2
0000-0002-7732-7023
Andres
Leschziner
University of California San Diego
La Jolla
California
United States
92093
0000-0002-7732-7023
Andres
Leschziner
University of California San Diego
La Jolla
California
United States
92093
Sanz Murillo M
Villagran Suarez A
Dederer V
Chatterjee D
Alegrio Louro J
Knapp S
Leschziner A
Michael J. Fox Foundation
ASAP-000519
United States
4.9
10.6019/EMPIAR-12702
EMDB
molecule
EMD-41728
Sanz Murillo M
Villagran Suarez A
Dederer V
Chatterjee D
Alegrio Louro J
Knapp S
Mathea S
Leschziner AE
Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures
Science advances
Sci Adv
48
9
2023
English
10.1126/sciadv.adk6191
38039358
micrographs taken with a 0.822A/px with 44 frames with a total dose of 56.9
Sanz Murillo M
Villagran Suarez A
Dederer V
Chatterjee D
Alegrio Louro J
Knapp S
Mathea S
Leschziner AE
Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures
Science advances
Sci Adv
48
9
2023
English
10.1126/sciadv.adk6191
38039358
Unaligned multiframe micrographs
/data/frames
micrographs - multiframe
MRC
MRC
5189
40
UNSIGNED BYTE
5760
0.822
4092
0.822