REL
2018-10-17
2019-02-20
2021-08-06
Cryo electron microscopy of tau filaments from sporadic Alzheimer's disease brain
0000-0002-0462-6540
Sjors
Scheres
MRC Laboratory of Molecular Biology
Cambridge
United Kingdom
CB2 0QH
0000-0002-8176-2618
Benjamin
Falcon
MRC Laboratory of Molecular Biology
Cambridge
United Kingdom
CB2 0QH
Michel
Goedert
MRC Laboratory of Molecular Biology
Cambridge
United Kingdom
CB2 0QH
Falcon B
Zhang W
Schweighauser M
Murzin AG
Vidal R
Garringer HJ
Ghetti B
Scheres SHW
Goedert M
27.0
10.6019/EMPIAR-10230
EMDB
EMD-0259
Falcon B
Zhang W
Schweighauser M
Murzin AG
Vidal R
Garringer HJ
Ghetti B
Scheres SHW
Goedert M
Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold
Acta neuropathologica
Acta Neuropathol.
5
136
699
708
2018
English
10.1007/s00401-018-1914-z
30276465
Dose-weighted micrographs of tau filaments from sporadic Alzheimer's disease brain (case 2)
/data/AD_patient2_EMPIAR/DW_Micrographs
micrographs - single frame
MRC
MRC
507
1
32 BIT FLOAT
variable
1.15
variable
1.15
Start- and end-points of filaments for PHFs and SFs written out as tube coordinate .star files with the following syntax (ignore comments after //):
data_
loop_
_rlnCoordinateX #1
_rlnCoordinateY #2
110.000000 1080.000000 // Tube 1 starting coordinates x, y
1855.000000 585.000000 // Tube 1 end coordinates x, y
635.000000 1325.000000 // Tube 2
560.000000 2490.000000
...
data/*/DW_Micrographs/*.mrc
data/*/Coordinates/*.star
data/AD_patient2_EMPIAR/Coordinates