<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-10671" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2021-03-19</depositionDate>
            <releaseDate>2021-04-15</releaseDate>
            <updateDate>2021-04-15</updateDate>
        </keyDates>
        <title>CryoEM structure of the CGRP receptor with bound CGRP peptide in a detergent micelle</title>
        <correspondingAuthor>
            <authorORCID>0000-0001-6406-8993</authorORCID>
            <firstName>Radostin</firstName>
            <lastName>Danev</lastName>
            <organization type="academic">The University of Tokyo</organization>
            <street>7-3-1 Hongo, Bunkyo-ku</street>
            <townOrCity>Toyko</townOrCity>
            <stateOrProvince>Tokyo</stateOrProvince>
            <country>Japan</country>
            <postOrZipCode>113-0033</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator>
            <authorORCID>0000-0001-8902-2473</authorORCID>
            <firstName>Patrick</firstName>
            <lastName>Sexton</lastName>
            <organization type="academic">Drug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University</organization>
            <street>399 Royal Parade</street>
            <townOrCity>Parkville</townOrCity>
            <stateOrProvince>Victoria</stateOrProvince>
            <country>Australia</country>
            <postOrZipCode>3052</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0002-7799-3683">Josephs TM</author>
            <author authorORCID="0000-0002-3229-474X">Belousoff MJ</author>
            <author authorORCID="0000-0001-6948-5550">Liang YL</author>
            <author authorORCID="0000-0001-5337-5197">Piper SJ</author>
            <author authorORCID="0000-0001-9160-0228">Cao J</author>
            <author authorORCID="0000-0002-4484-3603">Garama DJ</author>
            <author authorORCID="0000-0002-9280-1803">Leach K</author>
            <author authorORCID="0000-0002-3833-2137">Gregory KJ</author>
            <author authorORCID="0000-0003-4442-3294">Christopoulos A</author>
            <author authorORCID="0000-0002-9558-5122">Hay DL</author>
            <author authorORCID="0000-0001-6406-8993">Danev R</author>
            <author authorORCID="0000-0003-4563-1642">Wootten D</author>
            <author authorORCID="0000-0001-8902-2473">Sexton PM</author>
        </authorsList>
        <datasetSize units="TB">1.6</datasetSize>
        <entryDOI>10.6019/EMPIAR-10671</entryDOI>
        <experimentType>EMDB</experimentType>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-22963</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0002-7799-3683" order="1">Josephs TM</author>
                    <author authorORCID="0000-0002-3229-474X" order="2">Belousoff MJ</author>
                    <author authorORCID="0000-0001-6948-5550" order="3">Liang YL</author>
                    <author authorORCID="0000-0001-5337-5197" order="4">Piper SJ</author>
                    <author authorORCID="0000-0001-9160-0228" order="5">Cao J</author>
                    <author authorORCID="0000-0002-4484-3603" order="6">Garama DJ</author>
                    <author authorORCID="0000-0002-9280-1803" order="7">Leach K</author>
                    <author authorORCID="0000-0002-3833-2137" order="8">Gregory KJ</author>
                    <author authorORCID="0000-0003-4442-3294" order="9">Christopoulos A</author>
                    <author authorORCID="0000-0002-9558-5122" order="10">Hay DL</author>
                    <author authorORCID="0000-0001-6406-8993" order="11">Danev R</author>
                    <author authorORCID="0000-0003-4563-1642" order="12">Wootten D</author>
                    <author authorORCID="0000-0001-8902-2473" order="13">Sexton PM</author>
                    <title>Structure and dynamics of the CGRP receptor in apo and peptide-bound forms</title>
                    <journal>Science (New York, N.Y.)</journal>
                    <journalAbbreviation>Science</journalAbbreviation>
                    <country></country>
                    <year>2021</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1126/science.abf7258</externalReferences>
                    <externalReferences type="pubmed">33602864</externalReferences>
                    <details>Non-gain-normalized movies in compressed TIFF format. See the "Dataset_details_CGRPR-CGRP.txt" file for details.</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Non-gain-normalized LZW-TIFF compressed movies of CGRPR-CGRP in a detergent micelle</name>
        <directory>/data/PS0114.RAMP1-CGRP.2</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>5598</numImagesOrTiltSeries>
        <framesPerImage>71</framesPerImage>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>5760</imageWidth>
            <pixelWidth>0.83</pixelWidth>
            <imageHeight>4092</imageHeight>
            <pixelHeight>0.83</pixelHeight>
        </dimensions>
        <details>The "CGRPR-CGRP_data.star" file from the last 3D auto-refinement in Relion contains the particle coordinates and CTF parameters. The text file "Dataset_details_CGRPR-CGRP.txt" contains details about the experiment.</details>
        <segmentationList/>
        <micrographsFilePattern>data/PS0114.RAMP1-CGRP.2/*.tif</micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
