<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-10673" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2021-03-22</depositionDate>
            <releaseDate>2021-06-04</releaseDate>
            <updateDate>2021-06-04</updateDate>
        </keyDates>
        <title>Cryo-EM of GLP-1 receptor bound to GLP-1 and Gs protein</title>
        <correspondingAuthor>
            <authorORCID>0000-0001-6406-8993</authorORCID>
            <firstName>Radostin</firstName>
            <lastName>Danev</lastName>
            <organization type="academic">The University of Tokyo</organization>
            <street>7-3-1 Hongo, Bunkyo-ku</street>
            <townOrCity>Toyko</townOrCity>
            <stateOrProvince>Tokyo</stateOrProvince>
            <country>Japan</country>
            <postOrZipCode>113-0033</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator>
            <authorORCID>0000-0001-8902-2473</authorORCID>
            <firstName>Patrick</firstName>
            <lastName>Sexton</lastName>
            <organization type="academic">Drug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University</organization>
            <street>399 Royal Parade</street>
            <townOrCity>Parkville</townOrCity>
            <stateOrProvince>Victoria</stateOrProvince>
            <country>Australia</country>
            <postOrZipCode>3052</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author>Zhang X</author>
            <author authorORCID="0000-0002-3229-474X">Belousoff MJ</author>
            <author>Zhao P</author>
            <author authorORCID="0000-0001-5514-6021">Kooistra AJ</author>
            <author>Truong TT</author>
            <author>Ang SY</author>
            <author>Underwood CR</author>
            <author>Egebjerg T</author>
            <author>Šenel P</author>
            <author>Stewart GD</author>
            <author>Liang YL</author>
            <author>Glukhova A</author>
            <author>Venugopal H</author>
            <author>Christopoulos A</author>
            <author>Furness SGB</author>
            <author>Miller LJ</author>
            <author>Reedtz-Runge S</author>
            <author>Langmead CJ</author>
            <author authorORCID="0000-0002-4299-7561">Gloriam DE</author>
            <author authorORCID="0000-0001-6406-8993">Danev R</author>
            <author authorORCID="0000-0001-8902-2473">Sexton PM</author>
            <author authorORCID="0000-0003-4563-1642">Wootten D</author>
        </authorsList>
        <datasetSize units="TB">1.9</datasetSize>
        <entryDOI>10.6019/EMPIAR-10673</entryDOI>
        <experimentType>EMDB</experimentType>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-21992</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author order="1">Zhang X</author>
                    <author authorORCID="0000-0002-3229-474X" order="2">Belousoff MJ</author>
                    <author order="3">Zhao P</author>
                    <author authorORCID="0000-0001-5514-6021" order="4">Kooistra AJ</author>
                    <author order="5">Truong TT</author>
                    <author order="6">Ang SY</author>
                    <author order="7">Underwood CR</author>
                    <author order="8">Egebjerg T</author>
                    <author order="9">Šenel P</author>
                    <author order="10">Stewart GD</author>
                    <author order="11">Liang YL</author>
                    <author order="12">Glukhova A</author>
                    <author order="13">Venugopal H</author>
                    <author order="14">Christopoulos A</author>
                    <author order="15">Furness SGB</author>
                    <author order="16">Miller LJ</author>
                    <author order="17">Reedtz-Runge S</author>
                    <author order="18">Langmead CJ</author>
                    <author authorORCID="0000-0002-4299-7561" order="19">Gloriam DE</author>
                    <author authorORCID="0000-0001-6406-8993" order="20">Danev R</author>
                    <author authorORCID="0000-0001-8902-2473" order="21">Sexton PM</author>
                    <author authorORCID="0000-0003-4563-1642" order="22">Wootten D</author>
                    <title>Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists</title>
                    <journal>Molecular cell</journal>
                    <journalAbbreviation>Mol Cell</journalAbbreviation>
                    <country></country>
                    <issue>3</issue>
                    <volume>80</volume>
                    <firstPage>485</firstPage>
                    <lastPage>500.e7</lastPage>
                    <year>2020</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1016/j.molcel.2020.09.020</externalReferences>
                    <externalReferences type="pubmed">33027691</externalReferences>
                    <details>Check the "Dataset_details_GLP-1R-GLP-1.txt" file for details about the experiment and the dataset.</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Non-gain-normalized LZW-TIFF compressed movies of GLP-1R-GLP-1 in a detergent micelle</name>
        <directory>/data/PS0829.GLP-GLP1.2</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>5739</numImagesOrTiltSeries>
        <framesPerImage>75</framesPerImage>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>5760</imageWidth>
            <pixelWidth>0.83</pixelWidth>
            <imageHeight>4092</imageHeight>
            <pixelHeight>0.83</pixelHeight>
        </dimensions>
        <details>The "Dataset_details_GLP-1R-GLP-1.txt" file contains details about the experiment and the dataset. The gain reference created from the dataset is "GLP-1_gain.mrc". The particles from the last 3D auto-refinement are in the file "GLP-1_data.star".</details>
        <segmentationList/>
        <micrographsFilePattern>data/PS0829.GLP-GLP1.2/*.tif</micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
