REL
2021-05-12
2022-03-14
2022-09-15
Cryo-EM of the human insulin receptor ectodomain in complex with an insulin analog with truncated B chain and enlongated A chain
Alan
D
Blakely
Department of Biochemistry, University of Utah
201 Presidents' Cir
Salt Lake City
UT
United States
84112
Helena
D
Safavi-Hemami
University of Copenhagen
Copenhagen
Denmark
2200
Christopher
Hill
Department of Biochemistry, University of Utah
Salt Lake City
United States
84112
Danny
Chou
Pediatrics - Endocrinology
Palo Alto
CA
United States
94304
Xiong X
Blakely A
Kim JH
Menting JG
Schäfer IB
Schubert HL
Agrawal R
Gutmann T
Delaine C
Zhang YW
Artik GO
Merriman A
Eckert D
Lawrence MC
Coskun Ü
Fisher SJ
Forbes BE
Safavi-Hemami H
Hill CP
Chou DH
11.7
10.6019/EMPIAR-10736
EMDB
molecule
EMD-23949
EMD-23950
EMD-23951
Forbes BE
Safavi-Hemami H
Hill CP
Chou DH
Symmetric and asymmetric receptor conformation continuum induced by a new insulin
Nature chemical biology
Nat Chem Biol
5
18
511
519
2022
English
10.1038/s41589-022-00981-0
35289328
Unaligned multi-frame micrographs (40 e-/A2 dose)
/data/movies-dose-40
micrographs - multiframe
MRC
MRC
7221
40
0
39
UNSIGNED 16 BIT INTEGER
3838
1.365
3710
1.365
Raw, uncurated cryo-EM movies. Not gain corrected. Use gain image matching pattern *-gain-ref.mrc
unaligned micrographs (60 e-/A2 dose)
/data/movies-dose-60
micrographs - multiframe
MRC
MRC
4078
40
0
39
UNSIGNED 16 BIT INTEGER
3838
1.365
3710
1.365
Raw, uncurated cryo-EM movies. Not gain corrected. Use gain image matching pattern *-gain-ref.mrc