<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-10825" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2021-06-10</depositionDate>
            <releaseDate>2021-11-02</releaseDate>
            <updateDate>2021-11-02</updateDate>
        </keyDates>
        <title>Cryo electron microscopy of ex-vivo murine SAA amyloid fibrils</title>
        <correspondingAuthor>
            <authorORCID>0000-0002-9442-460X</authorORCID>
            <firstName>Matthias</firstName>
            <lastName>Schmidt</lastName>
            <organization type="academic">Institute of Protein Biochemistry, Ulm University</organization>
            <street>Helmholtzstrasse 8/1</street>
            <townOrCity>Ulm</townOrCity>
            <country>Germany</country>
            <postOrZipCode>89081</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator>
            <firstName>Marcus</firstName>
            <lastName>Faendrich</lastName>
            <organization type="academic">Institute of Protein Biochemistry, Ulm University</organization>
            <street>Helmholtzstrasse 8/1</street>
            <townOrCity>Ulm</townOrCity>
            <country>Germany</country>
            <postOrZipCode>89081</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0002-9442-460X">Schmidt MS</author>
            <author authorORCID="0000-0003-2123-6816">Fändrich MF</author>
        </authorsList>
        <datasetSize>533.9</datasetSize>
        <entryDOI>10.6019/EMPIAR-10825</entryDOI>
        <experimentType>EMDB</experimentType>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-8910</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0002-1557-2621" order="1">Liberta F</author>
                    <author authorORCID="0000-0002-1731-516X" order="2">Loerch S</author>
                    <author authorORCID="0000-0001-8287-6898" order="3">Rennegarbe M</author>
                    <author order="4">Schierhorn A</author>
                    <author authorORCID="0000-0002-2756-4995" order="5">Westermark P</author>
                    <author order="6">Westermark GT</author>
                    <author authorORCID="0000-0003-1827-0482" order="7">Hazenberg BPC</author>
                    <author authorORCID="0000-0002-1506-909X" order="8">Grigorieff N</author>
                    <author authorORCID="0000-0003-2123-6816" order="9">Fändrich M</author>
                    <author authorORCID="0000-0002-9442-460X" order="10">Schmidt M</author>
                    <title>Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids</title>
                    <journal>Nature communications</journal>
                    <journalAbbreviation>Nat Commun</journalAbbreviation>
                    <country>Germany</country>
                    <issue>1</issue>
                    <volume>10</volume>
                    <year>2019</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1038/s41467-019-09033-z</externalReferences>
                    <externalReferences type="pubmed">30846696</externalReferences>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Unaligned multiframe micrographs of ex-vivo murine SAA1</name>
        <directory>/data/micrographs</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>1429</numImagesOrTiltSeries>
        <framesPerImage>40</framesPerImage>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>7676</imageWidth>
            <pixelWidth>0.675</pixelWidth>
            <imageHeight>7420</imageHeight>
            <pixelHeight>0.675</pixelHeight>
        </dimensions>
        <details>Data collection with a Titan Krios EM (300 kV) using a K2 Summit camera, 20 eV slit. Defocus range -1.3 to -5.5, exposure time 10.2 and 8 seconds, dose rate 1.967 e/A^2/sec (set 1), 2.521 e/A^2/sec (set 2), total dose 20 e/A^2.
CS = 2.7 mm, HT = 300 kV, AmpCnst = 0.07.
In addition, thumbnails, power-spectra (data/thumbnails) and the gain reference (data/gain_reference) of ex-vivo murine SAA1 micrographs can be found within this entry.</details>
        <segmentationList/>
        <micrographsFilePattern>data/micrographs/*/*_*_*.tif</micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
