REL
2021-10-09
2022-01-24
2022-01-24
Structure of pathological TDP-43 filaments from ALS with FTLD (Individual 2, frontal cortex)
0000-0002-8176-2618
Benjamin
Falcon
MRC Laboratory of Molecular Biology
Francis Crick Avenue
Cambridge
United Kingdom
CB2 0QH
0000-0002-8176-2618
Benjamin
Falcon
MRC Laboratory of Molecular Biology
Francis Crick Avenue
Cambridge
United Kingdom
CB2 0QH
Arseni D
Hasegawa M
Murzin AG
Kametani F
Arai M
Yoshida M
Ryskeldi-Falcon B
2.9
10.6019/EMPIAR-10832
EMDB
EMD-13710
Arseni D
Hasegawa M
Murzin AG
Kametani F
Arai M
Yoshida M
Ryskeldi-Falcon B
Structure of pathological TDP-43 filaments from ALS with FTLD
Nature
Nature
7891
601
139
143
2021
English
10.1038/s41586-021-04199-3
34880495
The files were written as gain-unnormalised integer MRC files by EPU and then converted to TIFF files by mrc2tif in the IMOD suite. During this process, the pixel size in the header was lost. The real pixel size is 0.93 Å/px. The dose rate is 0.9755 e/Å2/frame. Please use the gain.tiff file a gain reference without any rotation or flipping.
Start_end_coordinates contains start-end coordinates of the manually picked filaments.
Data.star is a STAR file with the metadata of the final refined segments.
Unaligned multiframe movies
/data/Individual_2_FCx/Movies
micrographs - multiframe
TIFF
TIFF
15991
41
UNSIGNED BYTE
5760
0.93
4092
0.93
The files were written as gain-unnormalised integer MRC files by EPU and then converted to TIFF files by mrc2tif in the IMOD suite. During this process, the pixel size in the header was lost. The real pixel size is 0.93 Å/px. The dose rate is 0.99 e/Å2/frame. Please use the gain.tiff file a gain reference without any rotation or flipping.
data/Individual_2_FCx/Movies/GridSquare_*/Data/*_fractions.tiff
data/Individual_2_FCx/Start_end_coordinates/GridSquare_*/Data/*_manualpick.star
data/Individual_2_FCx/Start_end_coordinates