REL
2022-01-08
2023-01-03
2023-01-03
Apo C-terminal half of LRRK2 (I2020T) bound to microtubule
0000-0003-1033-9270
Mariusz
Matyszewski
CMM, UCSD
9500 Gilman Dr, MC 0694
La Jolla
California
United States
92093
0000-0002-7732-7023
Andres
Leschziner
CMM, UCSD
9500 Gilman Dr, MC 0694
La Jolla
California
United States
92093
Matyszewski M
Leschziner AE
643.9
10.6019/EMPIAR-10924
EMDB
molecule
EMD-25674
Snead DM
Matyszewski M
Dickey AM
Lin YX
Leschziner AE
Reck-Peterson SL
Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules
Nature structural & molecular biology
Nat Struct Mol Biol
12
29
1196
1207
2022
English
10.1038/s41594-022-00863-y
36510024
Publication includes structures of the C-terminal half of LRRK2 (I2020T) bound to microtubules as filaments, as well a structure of the C-terminal half of LRRK1.
Unaligned multi-frame micrographs of apo microtubule bound C-terminus of Leucine Rich Repeat Kinase 2 (LRRK2) (I2020T)
/data
micrographs - multiframe
TIFF
TIFF
2379
50
UNSIGNED 16 BIT INTEGER
3710
1.16
3838
1.16
Contains data collected from 2 grids (19dec14f and 20aug12b). Each folder contains its own gain reference with the "_norm.mrc" suffix found in the references folder. Blank dark references are also included but are not needed for correction. Gain correction in cryosparc should work with default settings, while for motioncor2, please flip the image and apply no rotation.
Total dose is 55 e/A-2