Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation

REL 2022-04-06 2022-04-13 2022-04-13 Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation 0000-0003-2432-5419 David S. Eisenberg University of California, Los Angeles 611 Young Drive East LOS ANGELES CA United States 90095 0000-0003-2432-5419 David S. Eisenberg University of California, Los Angeles 611 Young Drive East LOS ANGELES CA United States 90095 Abskharon R Sawaya MR Boyer DR Cao Q Nguyen BA Cascio D Eisenberg DS 2.4 10.6019/EMPIAR-11004 EMDB EMD-25364 Abskharon R Cascio D Sawaya MR Boyer DR Eisenberg DS Cao Q Nguyen BA Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation Proceedings of the National Academy of Sciences of the United States of America PNAS United States April 12 119 1 10 2022 English 10.1073/pnas.2119952119 35377792

Unaligned K3 movies. 1.3 e-/A^2/frame.

Unaligned movies of recombinant tau amyloid fibrils formed in the presence of RNA /data micrographs - multiframe MRC MRC 4729 40 UNSIGNED BYTE 3838 1.06 3710 1.06

Pixel size 1.06 A/pix. Dose rate: 1.3 e/A^2/frame.