Cryo electron-microscopy of TMEM106B fibrils extracted from four FTLD-TDP patient brains

REL 2022-04-08 2022-05-27 2022-05-30 Cryo electron-microscopy of TMEM106B fibrils extracted from four FTLD-TDP patient brains 0000-0003-1433-4952 Yi Xiao Jiang University of California, Los Angeles Los Angeles California United States 90095 0000-0003-2432-5419 David S. Eisenberg University of California, Los Angeles Los Angeles California United States 90095 Jiang YX Cao Q Sawaya MR Abskharon R Ge P DeTure M Dickson DW Fu JY Ogorzalek Loo RR Loo JA Eisenberg DS 3.4 10.6019/EMPIAR-11041 EMDB EMD-24953 EMD-24954 EMD-24955 Jiang YX Cao Q Sawaya MR Abskharon R Ge P DeTure M Dickson DW Fu JY Loo RR Loo JA Eisenberg DS Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43 Nature Nature 2022 English 10.1038/s41586-022-04670-9 35344984 Unaligned multi-frame micrographs of TMEM106B amyloid fibrils extracted from FTLD-TDP donor 1 /data/Donor1_20210412 micrographs - multiframe TIFF TIFF 4079 36 UNSIGNED BYTE variable variable variable variable

Pixel size: 1.1 A/pixel, dose rate: ~1 e/A^2/frame

Unaligned multi-frame micrographs of TMEM106B amyloid fibrils extracted from FTLD-TDP donor 2 /data/Donor2_20210510 micrographs - multiframe TIFF TIFF 2026 36 UNSIGNED BYTE variable variable variable variable

Pixel size: 1.1 A/pixel, dose rate: ~1 e/A^2/frame

Unaligned multi-frame micrographs of TMEM106B amyloid fibrils extracted from FTLD-TDP donor 3 /data/Donor3_20210712 micrographs - multiframe TIFF TIFF 2043 36 UNSIGNED BYTE variable variable variable variable

Pixel size: 1.1 A/pixel, dose rate: ~1 e/A^2/frame

Unaligned multi-frame micrographs of TMEM106B amyloid fibrils extracted from FTLD-TDP donor 4 /data/Donor4_20210717 micrographs - multiframe TIFF TIFF 1069 36 UNSIGNED BYTE variable variable variable variable

Pixel size: 1.1 A/pixel, dose rate: ~1 e/A^2/frame