REL
2022-05-25
2022-06-07
2022-06-07
Cryo-EM structure of the gastric proton pump complexed with revaprazan
0000-0003-2681-5921
Kazuhiro
Abe
Cellular and Structural Physiology Institute, Nagoya University
1, Furo-cho, Chikusa-ku
Nagoya
Aichi
Japan
464-8601
0000-0003-2681-5921
Kazuhiro
Abe
Cellular and Structural Physiology Institute, Nagoya University
1, Furo-cho, Chikusa-ku
Nagoya
Aichi
Japan
464-8601
Abe K
Tanaka S
Morita M
Yamagishi T
2.1
10.6019/EMPIAR-11057
EMDB
EMD-32299
Tanaka S
Morita M
Yamagishi T
Madapally HV
Hayashida K
Khandelia H
Gerle C
Shigematsu H
Oshima A
Abe K
Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump
Journal of medicinal chemistry
J Med Chem
2022
English
10.1021/acs.jmedchem.2c00338
35604136
This deposition contains raw movies for the gastric proton pump complexed with revaprazan. Two datasets (Movie 5 and 7) were merged to yield the published map.
K3 movies for the gastric proton pump complexed with revaprazan - Movies_5
/data/7W4A_EDM32299/Movies_5
micrographs - multiframe
TIFF
TIFF
8431
50
1
50
UNSIGNED BYTE
5760
0.752
4092
0.752
HT: 300 kV
Cs: 2.7 mm
Flux: 1e/Å2/frame
Please use CountCDSRef_2021-10-03_05.10.16_210922_2_5_230-1_0000.mrc as a gain reference without rotation and flipping.
The four digits at the end of the file names (0000 to 0024) represent beam shift directions.
K3 movies for the gastric proton pump complexed with revaprazan - Movies_7
/data/7W4A_EDM32299/Movies_7
micrographs - multiframe
TIFF
TIFF
1525
50
1
50
UNSIGNED BYTE
5760
0.752
4092
0.752
HT: 300 kV
Cs: 2.7 mm
Flux: 1e/Å2/frame
Please use CountCDSRef_2021-10-02_08.42.47_10716A_3_133-3_0000.mrc as a gain reference without rotation and flipping.
The four digits at the end of the file names (0000 to 0024) represent beam shift directions.