<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-11084" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2021-11-15</depositionDate>
            <releaseDate>2022-09-20</releaseDate>
            <updateDate>2022-09-20</updateDate>
        </keyDates>
        <title>Human amino acid transporter EAAT2</title>
        <correspondingAuthor>
            <authorORCID>0000-0003-1813-7008</authorORCID>
            <firstName>Osamu</firstName>
            <lastName>Nureki</lastName>
            <organization type="academic">Graduate School of Science, The University of Tokyo</organization>
            <street>7-3-1</street>
            <townOrCity>Hongo, Bunkyo-ku</townOrCity>
            <stateOrProvince>Tokyo</stateOrProvince>
            <country>Japan</country>
            <postOrZipCode>113-0033</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator>
            <authorORCID>0000-0003-1813-7008</authorORCID>
            <firstName>Osamu</firstName>
            <lastName>Nureki</lastName>
            <organization type="academic">Graduate School of Science, The University of Tokyo</organization>
            <street>7-3-1</street>
            <townOrCity>Hongo, Bunkyo-ku</townOrCity>
            <stateOrProvince>Toyko</stateOrProvince>
            <country>Japan</country>
            <postOrZipCode>113-0033</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0002-2285-1098">Kato T</author>
            <author authorORCID="0000-0002-6186-6647">Kusakizako T</author>
            <author authorORCID="0000-0002-5442-7582">Yamashita K</author>
            <author authorORCID="0000-0001-7463-8398">Nishizawa T</author>
            <author authorORCID="0000-0003-1813-7008">Nureki O</author>
        </authorsList>
        <datasetSize units="TB">1.5</datasetSize>
        <entryDOI>10.6019/EMPIAR-11084</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-32098</emdbEntry>
            <emdbEntry>EMD-32097</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0002-2285-1098" order="1">Kato T</author>
                    <author authorORCID="0000-0002-6186-6647" order="2">Kusakizako T</author>
                    <author order="3">Jin C</author>
                    <author order="4">Zhou X</author>
                    <author authorORCID="0000-0002-6894-7239" order="5">Ohgaki R</author>
                    <author order="6">Quan L</author>
                    <author order="7">Xu M</author>
                    <author order="8">Okuda S</author>
                    <author order="9">Kobayashi K</author>
                    <author authorORCID="0000-0002-5442-7582" order="10">Yamashita K</author>
                    <author authorORCID="0000-0001-7463-8398" order="11">Nishizawa T</author>
                    <author authorORCID="0000-0001-8126-286X" order="12">Kanai Y</author>
                    <author authorORCID="0000-0003-1813-7008" order="13">Nureki O</author>
                    <editor order="1"> </editor>
                    <title>Structural insights into inhibitory mechanism of human excitatory amino acid transporter EAAT2</title>
                    <journal>Nature communications</journal>
                    <journalAbbreviation>Nat Commun</journalAbbreviation>
                    <country></country>
                    <issue>1</issue>
                    <volume>13</volume>
                    <year>2022</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1038/s41467-022-32442-6</externalReferences>
                    <externalReferences type="pubmed">35953475</externalReferences>
                </journalCitation>
            </universalCitation>
            <universalCitation>
                <journalCitation published="false" preprint="true">
                    <author authorORCID="0000-0002-2285-1098" order="1">Kato T</author>
                    <author authorORCID="0000-0002-6186-6647" order="2">Kusakizako T</author>
                    <author order="3">Jin C</author>
                    <author order="4">Quan L</author>
                    <author authorORCID="0000-0002-6894-7239" order="5">Ohgaki R</author>
                    <author order="6">Okuda S</author>
                    <author order="7">Kobayashi K</author>
                    <author authorORCID="0000-0002-5442-7582" order="8">Yamashita K</author>
                    <author authorORCID="0000-0001-7463-8398" order="9">Nishizawa T</author>
                    <author authorORCID="0000-0001-8126-286X" order="10">Kanai Y</author>
                    <author authorORCID="0000-0003-1813-7008" order="11">Nureki O</author>
                    <editor order="1"> </editor>
                    <title>Structural insights into inhibitory mechanism of human excitatory amino acid transporter EAAT2</title>
                    <journal>bioRxiv</journal>
                    <journalAbbreviation>bioRxiv</journalAbbreviation>
                    <country></country>
                    <year>2021</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1101/2021.11.03.465409</externalReferences>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Unaligned movies for apo structure</name>
        <directory>/data/190704_kato2</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>3351</numImagesOrTiltSeries>
        <framesPerImage>63</framesPerImage>
        <frameRange>
            <frameRangeMin>1</frameRangeMin>
            <frameRangeMax>63</frameRangeMax>
        </frameRange>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>5760</imageWidth>
            <pixelWidth>0.85</pixelWidth>
            <imageHeight>4092</imageHeight>
            <pixelHeight>0.85</pixelHeight>
        </dimensions>
        <details>300 kV
Cs 2.7 mm
Flux: 50e/A2 over 63 frames
Please use movie_gain.mrc as a gain reference without any rotation or flipping.
Four digits (0000 to 0008) in the file names represent the direction of beam shift.</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
    <imageSet>
        <name>Unaligned movies for the inhibitor bound structure</name>
        <directory>/data/190824_kato_inh</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>3274</numImagesOrTiltSeries>
        <framesPerImage>48</framesPerImage>
        <frameRange>
            <frameRangeMin>1</frameRangeMin>
            <frameRangeMax>48</frameRangeMax>
        </frameRange>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>5760</imageWidth>
            <pixelWidth>0.85</pixelWidth>
            <imageHeight>4092</imageHeight>
            <pixelHeight>0.85</pixelHeight>
        </dimensions>
        <details>300 kV
Cs 2.7 mm
Flux: 50e/A2 over 48 frames
Please use movie_gain.mrc as a gain reference without any rotation or flipping.
Four digits (0000 to 0008) in the file names represent the direction of beam shift.</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
