Micrographs of IAPP (amylin) amyloid fibrils

REL 2020-09-11 2022-07-27 2022-07-27 Micrographs of IAPP (amylin) amyloid fibrils 0000-0003-1803-5431 Gunnar F Schröder Forschungszentrum Jülich Jülich Germany 52425 0000-0003-1803-5431 Gunnar F Schröder Forschungszentrum Jülich Jülich Germany 52425 Röder C Schröder GF 83.1 10.6019/EMPIAR-11093 EMDB molecule EMD-10669 EMD-10670 EMD-10671 Röder C Kupreichyk T Gremer L Schäfer LU Pothula KR Ravelli RBG Willbold D Hoyer W Schröder GF Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-β fibrils Nature structural & molecular biology Nat. Struct. Mol. Biol. United Kingdom 7 27 660 667 2020 English 10.1038/s41594-020-0442-4 32541895 MotionCor2-aligned single frame of islet amyloid polypeptide fibrils /data micrographs - single frame MRC MRC 1330 1 32 BIT FLOAT 4096 0.935 4096 0.935

These data are aligned average micrographs collected on a Technai Arctica at 200kV with a Falcon III detector operating in electron counting mode. Applied defocus values ranged from −1 to −2.2 µm. MotionCor2 was used to align 50 dose fractions that were taken with a total electron dose of ~42e-/Å².