REL
2022-08-20
2022-09-09
2022-09-09
Cryo-electron microscopy of human exostosin-like 3 (EXTL3) in the presence of UDP
0000-0001-6438-3328
Louis
Frederick Lundy
Wilson
Department of Molecular Physiology and Biophysics, University of Virginia
480 Ray C Hunt Drive
Charlottesville
Virginia
United States
22903
0000-0001-9270-6286
Paul
Dupree
Department of Biochemistry, University of Cambridge
Hopkins Building, Tennis Court Road
Cambridge
Cambridgeshire
United Kingdom
CB2 1QW
0000-0002-1821-0634
Katrin
Mani
Department of Experimental Medical Science, Division of Neuroscience, Glycobiology Group, Lund University
Lund
Sweden
SE-221 00
Wilson LFL
Dendooven T
Hardwick SW
EchevarrÃa-Poza A
Tryfona T
Krogh KBRM
Chirgadze DY
Luisi BF
Logan DT
Mani K
Dupree P
6.7
10.6019/EMPIAR-11182
EMDB
molecule
EMD-11926
Wilson LFL
Dendooven T
Hardwick SW
EchevarrÃa-Poza A
Tryfona T
Krogh KBRM
Chirgadze DY
Luisi BF
Logan DT
Mani K
Dupree P
The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis
Nature communications
Nat Commun
1
13
2022
English
10.1038/s41467-022-31048-2
35676258
Raw frames from cryo-EM movies for SPA. 50 frames per movie, 0.969 e/A^2 dose per frame. 1.065 A pixel size. 300 kV.
Unaligned multi-frame micrographs of EXTL3 (residues 52-919) in complex with UDP
/data
micrographs - multiframe
MRC
MRC
2573
1
32 BIT FLOAT
3838
1.065
3710
1.065