<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-11267" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2022-08-23</depositionDate>
            <releaseDate>2022-11-07</releaseDate>
            <updateDate>2022-11-07</updateDate>
        </keyDates>
        <title>Topological Crossing in the Misfolded Tetrahymena Ribozyme Resolved by Cryo-EM</title>
        <correspondingAuthor>
            <authorORCID>0000-0003-0414-4776</authorORCID>
            <firstName>Kaiming</firstName>
            <lastName>Zhang</lastName>
            <organization type="academic">University of Science and Technology of China</organization>
            <townOrCity>Hefei</townOrCity>
            <stateOrProvince>Anhui</stateOrProvince>
            <country>China</country>
            <postOrZipCode>230027</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator>
            <authorORCID>0000-0003-0414-4776</authorORCID>
            <firstName>Kaiming</firstName>
            <lastName>Zhang</lastName>
            <organization type="academic">University of Science and Technology of China</organization>
            <townOrCity>Hefei</townOrCity>
            <stateOrProvince>Anhui</stateOrProvince>
            <country>China</country>
            <postOrZipCode>230027</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0002-7041-5960">Li S</author>
            <author authorORCID="0000-0003-4883-6766">Palo M</author>
            <author authorORCID="0000-0002-0848-5335">Pintilie GD</author>
            <author authorORCID="0000-0001-8424-3824">Zhang X</author>
            <author authorORCID="0000-0002-9279-1721">Su Z</author>
            <author authorORCID="0000-0002-2129-199X">Kappel K</author>
            <author authorORCID="0000-0002-8910-3078">Chiu W</author>
            <author authorORCID="0000-0003-0414-4776">Zhang K</author>
            <author authorORCID="0000-0001-7497-0972">Das R</author>
        </authorsList>
        <datasetSize units="TB">3.6</datasetSize>
        <entryDOI>10.6019/EMPIAR-11267</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-33425</emdbEntry>
            <emdbEntry>EMD-33426</emdbEntry>
            <emdbEntry>EMD-33427</emdbEntry>
            <emdbEntry>EMD-33428</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0002-7041-5960" order="1">Li S</author>
                    <author authorORCID="0000-0003-4883-6766" order="2">Palo M</author>
                    <author authorORCID="0000-0002-0848-5335" order="3">Pintilie GD</author>
                    <author authorORCID="0000-0001-8424-3824" order="4">Zhang X</author>
                    <author authorORCID="0000-0002-9279-1721" order="5">Su Z</author>
                    <author authorORCID="0000-0002-2129-199X" order="6">Kappel K</author>
                    <author authorORCID="0000-0002-8910-3078" order="7">Chiu W</author>
                    <author authorORCID="0000-0003-0414-4776" order="8">Zhang K</author>
                    <author authorORCID="0000-0001-7497-0972" order="9">Das R</author>
                    <title>Topological crossing in the misfolded &lt;i&gt;Tetrahymena&lt;/i&gt; ribozyme resolved by cryo-EM</title>
                    <journal>Proceedings of the National Academy of Sciences of the United States of America</journal>
                    <journalAbbreviation>Proc Natl Acad Sci U S A</journalAbbreviation>
                    <country></country>
                    <issue>37</issue>
                    <volume>119</volume>
                    <year>2022</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1073/pnas.2209146119</externalReferences>
                    <externalReferences type="pubmed">36067294</externalReferences>
                    <details>The motion-corrected images of misfolded Tetrahymena Ribozyme</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Misfolded Tetrahymena ribozyme</name>
        <directory>/data</directory>
        <category>micrographs - single frame</category>
        <headerFormat>MRC</headerFormat>
        <dataFormat>MRC</dataFormat>
        <numImagesOrTiltSeries>42382</numImagesOrTiltSeries>
        <framesPerImage>1</framesPerImage>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>5760</imageWidth>
            <pixelWidth>0.82</pixelWidth>
            <imageHeight>4092</imageHeight>
            <pixelHeight>variable</pixelHeight>
        </dimensions>
        <details>Motion corrected micrographs. The large single particle cryo-EM dataset of misfolded Tetrahymena ribozyme.</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
