Tau Paired Helical Filament from Alzheimer's Disease incubated with EGCG for 3 hours

REL 2022-11-10 2022-11-21 2022-11-21 Tau Paired Helical Filament from Alzheimer's Disease incubated with EGCG for 3 hours 0000-0002-2661-8226 Peng Ge Howard Hughes Medical Institute; Department of Chemistry and Biochemistry, UCLA Los Angeles California United States 90095 0000-0003-2432-5419 David S Eisenberg Department of Chemistry and Biochemistry, and Department of Biological Chemistry, UCLA; HHMI Los Angeles California United States 90095 Seidler PM Murray KA Boyer DR Ge P Sawaya MR Eisenberg DS 1.7 10.6019/EMPIAR-11301 EMDB molecule EMD-26665 Seidler PM Murray KA Boyer DR Ge P Sawaya MR Hu CJ Cheng X Abskharon R Pan H DeTure MA Williams CK Diskson DW Vinters HV Eisenberg DS Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro Nature communications Nat Commun 1 13 5451 12 2022 English 10.1038/s41467-022-32951-4 36114178

Raw movies with 30 frames each. Total dosage is 18 e/A2. Gain reference provided.

Unaligned multi-frame movies /data/Movies micrographs - multiframe MRCS MRCS 6406 30 UNSIGNED BYTE 7676 0.532 7420 0.532

Total dosage for each movie is 18 e/A^2.