<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-11508" schemaVersion="0.63" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2023-04-14</depositionDate>
            <releaseDate>2023-06-09</releaseDate>
            <updateDate>2023-06-09</updateDate>
        </keyDates>
        <title>CryoEM movies of extracted Arctic variant Aß42 fibrils from mouse brains labelled with methoxy-X04</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0001-9724-9547</authorORCID>
            <firstName>René</firstName>
            <middleName>AW</middleName>
            <lastName>Frank</lastName>
            <organization type="academic">University of Leeds</organization>
            <street>Woodhouse</street>
            <townOrCity>Leeds</townOrCity>
            <stateOrProvince>Yorkshire</stateOrProvince>
            <country>United Kingdom</country>
            <postOrZipCode>LS2 9JT</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0001-9724-9547</authorORCID>
            <firstName>René</firstName>
            <middleName>AW</middleName>
            <lastName>Frank</lastName>
            <organization type="academic">University of Leeds</organization>
            <street>Woodhouse</street>
            <townOrCity>Leeds</townOrCity>
            <country>United Kingdom</country>
            <postOrZipCode>LS2 9JT</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author>Leistner C</author>
            <author authorORCID="0000-0001-5490-613X">Wilkinson M</author>
            <author authorORCID="0000-0002-9643-3163">Burgess A</author>
            <author authorORCID="0000-0002-7171-0494">Lovatt M</author>
            <author>Goodbody S</author>
            <author authorORCID="0000-0002-8389-4120">Xu Y</author>
            <author authorORCID="0000-0002-1876-3239">Deuchars S</author>
            <author authorORCID="0000-0002-3079-8039">Radford SE</author>
            <author authorORCID="0000-0002-3640-5275">Ranson NA</author>
            <author authorORCID="0000-0001-9724-9547">Frank RAW</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody>Medical Research Council (MRC, United Kingdom)</fundingBody>
                <code>MR/T011149/1</code>
                <country>United Kingdom</country>
            </grantReference>
            <grantReference>
                <fundingBody>Wellcome Trust</fundingBody>
                <code>204963</code>
                <country>United Kingdom</country>
            </grantReference>
            <grantReference>
                <fundingBody>UK Research and Innovation (UKRI)</fundingBody>
                <code>MR/V022644/1</code>
                <country>United Kingdom</country>
            </grantReference>
        </grantSupport>
        <datasetSize units="GB">648.2</datasetSize>
        <entryDOI>10.6019/EMPIAR-11508</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-16019</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author order="1">Leistner C</author>
                    <author authorORCID="0000-0001-5490-613X" order="2">Wilkinson M</author>
                    <author authorORCID="0000-0002-9643-3163" order="3">Burgess A</author>
                    <author authorORCID="0000-0002-7171-0494" order="4">Lovatt M</author>
                    <author order="5">Goodbody S</author>
                    <author authorORCID="0000-0002-8389-4120" order="6">Xu Y</author>
                    <author authorORCID="0000-0002-1876-3239" order="7">Deuchars S</author>
                    <author authorORCID="0000-0002-3079-8039" order="8">Radford SE</author>
                    <author authorORCID="0000-0002-3640-5275" order="9">Ranson NA</author>
                    <author authorORCID="0000-0001-9724-9547" order="10">Frank RAW</author>
                    <title>The in-tissue molecular architecture of β-amyloid pathology in the mammalian brain</title>
                    <journal>Nature communications</journal>
                    <journalAbbreviation>Nat Commun</journalAbbreviation>
                    <country></country>
                    <issue>1</issue>
                    <volume>14</volume>
                    <year>2023</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1038/s41467-023-38495-5</externalReferences>
                    <externalReferences type="pubmed">37198197</externalReferences>
                    <details>4,165 tif movies are supplied, each containing 40 frames with a dose per frame of ~1.0 e-/Å2</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Unaligned Tif movie frames of Arctic abeta42 from mouse brains labelled with Methoxy-X04</name>
        <directory>/data/Movies_Tifs</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>4165</numImagesOrTiltSeries>
        <framesPerImage>40</framesPerImage>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>4096</imageWidth>
            <pixelWidth>0.94</pixelWidth>
            <imageHeight>4096</imageHeight>
            <pixelHeight>0.94</pixelHeight>
        </dimensions>
        <details></details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
