REL
2023-04-14
2023-09-22
2023-09-22
In-tissue cryo electron tomography of App^NL-G-F amyloid plaques
0000-0001-9724-9547
René
AW
Frank
University of Leeds
Woodhouse
Leeds
Yorkshire
United Kingdom
LS2 9JT
0000-0001-9724-9547
René
AW
Frank
University of Leeds
Woodhouse
Leeds
United Kingdom
LS2 9JT
Leistner C
Wilkinson M
Burgess A
Lovatt M
Goodbody S
Xu Y
Deuchars S
Radford SE
Ranson NA
Frank RAW
Medical Research Council (MRC, United Kingdom)
MR/T011149/1
United Kingdom
Wellcome Trust
204963
United Kingdom
UK Research and Innovation (UKRI)
MR/V022644/1
United Kingdom
38.0
10.6019/EMPIAR-11509
EMDB
tissue
EMD-18301
EMD-16018
Leistner C
Wilkinson M
Burgess A
Lovatt M
Goodbody S
Xu Y
Deuchars S
Radford SE
Ranson NA
Frank RAW
The in-tissue molecular architecture of β-amyloid pathology in the mammalian brain
Nature communications
Nat Commun
1
14
2023
English
10.1038/s41467-023-38495-5
37198197
Unaligned tilt series of MX04-labelled amyloid plaques in CEMOVIS/cryo-sections from ~1yr old App^NL-G-F mouse cortex
Summed, unaligned tilt series
/data/tiltseries
tilt series
MRC
MRC
23
61
UNSIGNED 16 BIT INTEGER
3710
3.421
3838
3.421
Summed, unaligned tilt series from 23 tomograms, -60 to +60˚, 2˚ increments, 85.8˚ microscope rotation angle (hand unknown), ~1 e-/Å2 dose per tilt.
Corresponding CryoCLEM images are also supplied