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        <keyDates>
            <depositionDate>2023-08-04</depositionDate>
            <releaseDate>2023-10-03</releaseDate>
            <updateDate>2023-10-03</updateDate>
        </keyDates>
        <title>Single particle cryo-EM dataset of mitochondrial complex I from Mus musculus inhibited by IACS-2858 - 2</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0001-6890-6050</authorORCID>
            <firstName>Hannah</firstName>
            <middleName>Ruth</middleName>
            <lastName>Bridges</lastName>
            <organization type="academic">MRC Mitochondrial Biology Unit</organization>
            <street>Hills Road</street>
            <townOrCity>Cambridge</townOrCity>
            <stateOrProvince>Cambridgeshire</stateOrProvince>
            <country>United Kingdom</country>
            <postOrZipCode>CB2 0XY</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0001-8667-6797</authorORCID>
            <firstName>Judy</firstName>
            <lastName>Hirst</lastName>
            <organization type="academic">MRC Mitochondrial Biology Unit</organization>
            <street>Hills Road</street>
            <townOrCity>Cambridge</townOrCity>
            <stateOrProvince>Cambridgeshire</stateOrProvince>
            <country>United Kingdom</country>
            <postOrZipCode>CB2 0XY</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0002-2902-4677">Chung I</author>
            <author authorORCID="0000-0001-8667-6797">Hirst J</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody>Medical Research Council (MRC, United Kingdom)</fundingBody>
                <code>MC_UU_00015/2</code>
                <country>United Kingdom</country>
            </grantReference>
            <grantReference>
                <fundingBody>Medical Research Council (MRC, United Kingdom)</fundingBody>
                <code>MC_U105663141</code>
                <country>United Kingdom</country>
            </grantReference>
        </grantSupport>
        <datasetSize units="GB">757.2</datasetSize>
        <entryDOI>10.6019/EMPIAR-11656</entryDOI>
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        <scale>molecule</scale>
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    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-12095</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0002-2902-4677" order="1">Chung I</author>
                    <author order="2">Serreli R</author>
                    <author order="3">Cross JB</author>
                    <author order="4">Di Francesco ME</author>
                    <author order="5">Marszalek JR</author>
                    <author authorORCID="0000-0001-8667-6797" order="6">Hirst J</author>
                    <title>Cork-in-bottle mechanism of inhibitor binding to mammalian complex I.</title>
                    <journal>Science advances</journal>
                    <journalAbbreviation>Sci Adv</journalAbbreviation>
                    <country></country>
                    <issue>20</issue>
                    <volume>7</volume>
                    <year>2021</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1126/sciadv.abg4000</externalReferences>
                    <externalReferences type="pubmed">33990335</externalReferences>
                    <details>571 gain-corrected mrc movies containing 25 frames with a total dose of 58.4 e/A^2</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Unaligned, gain-corrected micrographs of mitochondrial complex I from mouse heart inhibited with IACS-2858</name>
        <directory>/data</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>MRC</headerFormat>
        <dataFormat>MRC</dataFormat>
        <numImagesOrTiltSeries>571</numImagesOrTiltSeries>
        <framesPerImage>25</framesPerImage>
        <frameRange>
            <frameRangeMin>1</frameRangeMin>
            <frameRangeMax>25</frameRangeMax>
        </frameRange>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>3838</imageWidth>
            <pixelWidth>1.055</pixelWidth>
            <imageHeight>3710</imageHeight>
            <pixelHeight>1.055</pixelHeight>
        </dimensions>
        <details>Micrographs are the average of 25 unaligned, gain-corrected frames. Images were collected on a Krios with a K2 detector and energy filter with a slit width of 20eV. Data were collected over 10 seconds with a dose rate of 5.84 e / A-2 / s with a total dose of 58.4 e/A-2.</details>
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        <micrographsFilePattern>data/*.mrc</micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
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