<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-11716" schemaVersion="0.65" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2023-08-03</depositionDate>
            <releaseDate>2024-04-17</releaseDate>
            <updateDate>2024-04-17</updateDate>
        </keyDates>
        <title>CryoEM movies of IAPP-S20G timecourse (3 week repeat, FT14)</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0002-3640-5275</authorORCID>
            <firstName>Neil</firstName>
            <lastName>Ranson</lastName>
            <organization type="academic">University of Leeds, School of Molecular &amp;amp; Cellular Biology</organization>
            <street>Willow Terrace Road</street>
            <townOrCity>Leeds</townOrCity>
            <country>United Kingdom</country>
            <postOrZipCode>LS2 9JT</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0002-3640-5275</authorORCID>
            <firstName>Neil</firstName>
            <middleName>A</middleName>
            <lastName>Ranson</lastName>
            <organization type="academic">University of Leeds</organization>
            <street>Willow Terrace Road</street>
            <townOrCity>Leeds</townOrCity>
            <country>United Kingdom</country>
            <postOrZipCode>LS2 9JT</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0001-5490-613X">Wilkinson M</author>
            <author>Xu Y</author>
            <author authorORCID="0000-0001-6171-9703">Thacker D</author>
            <author authorORCID="0000-0003-3131-3619">Taylor AIP</author>
            <author>Fisher DG</author>
            <author authorORCID="0000-0003-1584-3564">Gallardo RU</author>
            <author authorORCID="0000-0002-3079-8039">Radford SE</author>
            <author authorORCID="0000-0002-3640-5275">Ranson NA</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody>Medical Research Council (MRC, United Kingdom)</fundingBody>
                <code>MR/T011149/1</code>
                <country>United Kingdom</country>
            </grantReference>
            <grantReference>
                <fundingBody>Wellcome Trust</fundingBody>
                <code>204963</code>
                <country>United Kingdom</country>
            </grantReference>
        </grantSupport>
        <datasetSize units="GB">308.5</datasetSize>
        <entryDOI>10.6019/EMPIAR-11716</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-15696</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0001-5490-613X" order="1">Wilkinson M</author>
                    <author order="2">Xu Y</author>
                    <author authorORCID="0000-0001-6171-9703" order="3">Thacker D</author>
                    <author authorORCID="0000-0003-3131-3619" order="4">Taylor AIP</author>
                    <author order="5">Fisher DG</author>
                    <author authorORCID="0000-0003-1584-3564" order="6">Gallardo RU</author>
                    <author authorORCID="0000-0002-3079-8039" order="7">Radford SE</author>
                    <author authorORCID="0000-0002-3640-5275" order="8">Ranson NA</author>
                    <title>Structural evolution of fibril polymorphs during amyloid assembly</title>
                    <journal>Cell</journal>
                    <journalAbbreviation>Cell</journalAbbreviation>
                    <country></country>
                    <issue>26</issue>
                    <volume>186</volume>
                    <firstPage>5798</firstPage>
                    <lastPage>5811.e26</lastPage>
                    <year>2023</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1016/j.cell.2023.11.025</externalReferences>
                    <externalReferences type="pubmed">38134875</externalReferences>
                    <details>Gain corrected, tif converted movies. There are 2317 total movies, each containing 40 frames, with a dose of 1.1 e-/Å2/frame.</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Unaligned tif movie stacks (gain corrected) for the IAPP-S20G 3 week repeat cryoEM dataset</name>
        <directory>/data/Movies_tifs</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>2317</numImagesOrTiltSeries>
        <framesPerImage>40</framesPerImage>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>4096</imageWidth>
            <pixelWidth>0.95</pixelWidth>
            <imageHeight>4096</imageHeight>
            <pixelHeight>0.95</pixelHeight>
        </dimensions>
        <details>Only unaligned movies are present. The total dose was 43 e-/Å2 over 40 frames. Structures could not be resolved from this dataset to high resolution</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
