<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-11740" schemaVersion="0.65" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2023-10-20</depositionDate>
            <releaseDate>2024-06-04</releaseDate>
            <updateDate>2024-06-04</updateDate>
        </keyDates>
        <title>Taf15, TMEM106B and Aß42 amyloid filaments - Individual 4, brainstem</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0002-8176-2618</authorORCID>
            <firstName>Benjamin</firstName>
            <lastName>Ryskeldi-Falcon</lastName>
            <organization type="academic">MRC Laboratory of Molecular Biology</organization>
            <street>Francis Crick Avenue</street>
            <townOrCity>Cambridge</townOrCity>
            <stateOrProvince>Cambridgeshire</stateOrProvince>
            <country>United Kingdom</country>
            <postOrZipCode>CB2 0QH</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0002-8176-2618</authorORCID>
            <firstName>Benjamin</firstName>
            <lastName>Ryskeldi-Falcon</lastName>
            <organization type="academic">MRC Laboratory of Molecular Biology</organization>
            <street>Francis Crick Avenue</street>
            <townOrCity>Cambridge</townOrCity>
            <stateOrProvince>Cambridgeshire</stateOrProvince>
            <country>United Kingdom</country>
            <postOrZipCode>CB2 0QH</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0002-4175-0225">Tetter S</author>
            <author authorORCID="0000-0001-7585-288X">Arseni D</author>
            <author>Murzin AG</author>
            <author authorORCID="0000-0002-6689-4508">Buhidma Y</author>
            <author authorORCID="0000-0002-7602-6384">Peak-Chew SY</author>
            <author authorORCID="0000-0002-1899-7676">Garringer HJ</author>
            <author authorORCID="0000-0002-1648-7357">Newell KL</author>
            <author authorORCID="0000-0002-5803-3871">Vidal R</author>
            <author>Apostolova LG</author>
            <author authorORCID="0000-0001-7389-0348">Lashley T</author>
            <author authorORCID="0000-0002-1842-8019">Ghetti B</author>
            <author authorORCID="0000-0002-8176-2618">Ryskeldi-Falcon B</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody></fundingBody>
                <code></code>
                <country></country>
            </grantReference>
        </grantSupport>
        <datasetSize units="GB">435.6</datasetSize>
        <entryDOI>10.6019/EMPIAR-11740</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-18227</emdbEntry>
            <emdbEntry>EMD-18226</emdbEntry>
            <emdbEntry>EMD-18243</emdbEntry>
            <emdbEntry>EMD-18241</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0002-4175-0225" order="1">Tetter S</author>
                    <author authorORCID="0000-0001-7585-288X" order="2">Arseni D</author>
                    <author order="3">Murzin AG</author>
                    <author authorORCID="0000-0002-6689-4508" order="4">Buhidma Y</author>
                    <author authorORCID="0000-0002-7602-6384" order="5">Peak-Chew SY</author>
                    <author authorORCID="0000-0002-1899-7676" order="6">Garringer HJ</author>
                    <author authorORCID="0000-0002-1648-7357" order="7">Newell KL</author>
                    <author authorORCID="0000-0002-5803-3871" order="8">Vidal R</author>
                    <author order="9">Apostolova LG</author>
                    <author authorORCID="0000-0001-7389-0348" order="10">Lashley T</author>
                    <author authorORCID="0000-0002-1842-8019" order="11">Ghetti B</author>
                    <author authorORCID="0000-0002-8176-2618" order="12">Ryskeldi-Falcon B</author>
                    <title>TAF15 amyloid filaments in frontotemporal lobar degeneration</title>
                    <journal>Nature</journal>
                    <journalAbbreviation>Nature</journalAbbreviation>
                    <country></country>
                    <issue>7994</issue>
                    <volume>625</volume>
                    <firstPage>345</firstPage>
                    <lastPage>351</lastPage>
                    <year>2023</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1038/s41586-023-06801-2</externalReferences>
                    <externalReferences type="pubmed">38057661</externalReferences>
                    <details>Raw movies, collected at a total does of 40 e/A2</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>amyloid filaments - Individual 4, brainstem</name>
        <directory>/data/Individual4_brainstem/movies</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>4682</numImagesOrTiltSeries>
        <framesPerImage>21</framesPerImage>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>4096</imageWidth>
            <pixelWidth>0.824</pixelWidth>
            <imageHeight>4096</imageHeight>
            <pixelHeight>0.824</pixelHeight>
        </dimensions>
        <details>The files were written as gain-unnormalised integer .tiff files by EPU. The gain reference is in the GainRef folder. The run_data.star file from the final 3D refinements are included in separate folders for each one of the four structures.</details>
        <segmentationList/>
        <micrographsFilePattern>data/Individual4_brainstem/movies/gain2/Supervisor_20230623_102420_27/Images-Disc1/*/*/*.tif</micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory>data/Individual4_brainstem/ManualPick</pickedParticlesDirectory>
    </imageSet>
</entry>
