REL 2024-02-21 2024-06-12 2024-06-12 0000-0003-2391-473X Yi-Wei Chang Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania 422 Curie Blvd Philadelphia PA United States 19104 0000-0003-2391-473X Yi-Wei Chang Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania Philadelphia PA United States 19104 0000-0002-4589-1180 Edward B Lee Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania 422 Curie Blvd Philadelphia PA United States 19104 Creekmore BC Kixmoeller K Black BE Lee EB Chang Y-W National Science Foundation (NSF, United States) DMR-2309043 United States National Institutes of Health (NIH) RF1AG065341 United States National Institutes of Health (NIH) P30AG072979 United States National Institutes of Health (NIH) P01AG066597 United States National Institutes of Health (NIH) U19AG062418 United States David and Lucile Packard Foundation 2019-69645 United States Burroughs Wellcome Fund 1022785 United States National Institutes of Health (NIH) RM1GM136511 United States National Institutes of Health (NIH) RM35GM130302 United States National Institutes of Health (NIH) T32GM132039 United States National Institutes of Health (NIH) F30AG077756 United States National Institutes of Health (NIH) F30CA261198 United States 3.2 10.6019/EMPIAR-11920 EMDB tissue EMD-43334 EMD-43330 EMD-43331 Creekmore BC Kixmoeller K Black BE Lee EB Chang YW Nature communications Nat Commun 1 15 2024 English 10.1038/s41467-024-47066-1 38531877 Tilt series of human Alzheimer's disease brain tissue /data tilt series MRC MRC 3 1 SIGNED 16 BIT INTEGER 5760 2.674 4092 2.674