<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-12121" schemaVersion="0.65" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2024-06-06</depositionDate>
            <releaseDate>2024-07-19</releaseDate>
            <updateDate>2024-07-19</updateDate>
        </keyDates>
        <title>Particle stacks from heart-derived AL amyloid (AL59) cryo-EM data</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0003-3287-9024</authorORCID>
            <firstName>Antonio</firstName>
            <lastName>Chaves-Sanjuan</lastName>
            <organization type="academic">Department of Biosciences, University of Milan</organization>
            <townOrCity>Milan</townOrCity>
            <country>Italy</country>
            <postOrZipCode>20133</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0003-3287-9024</authorORCID>
            <firstName>Antonio</firstName>
            <lastName>Chaves-Sanjuan</lastName>
            <organization type="academic">Department of Biosciences, University of Milan</organization>
            <townOrCity>Milan</townOrCity>
            <country>Italy</country>
            <postOrZipCode>20133</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0002-7322-8933">Schulte T</author>
            <author authorORCID="0000-0002-7219-3097">Speranzini V</author>
            <author authorORCID="0000-0003-3287-9024">Chaves-Sanjuan A</author>
            <author authorORCID="0009-0000-7726-8580">Milazzo M</author>
            <author authorORCID="0000-0001-6678-5873">Ricagno S</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody>Ministero dell Universita e della Ricerca</fundingBody>
                <code>PRIN 2020 (20207XLJB2)</code>
                <country>Italy</country>
            </grantReference>
        </grantSupport>
        <datasetSize units="GB">130.1</datasetSize>
        <entryDOI>10.6019/EMPIAR-12121</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-50270</emdbEntry>
            <emdbEntry>EMD-50271</emdbEntry>
            <emdbEntry>EMD-50272</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="false" preprint="false">
                    <author authorORCID="0000-0002-7322-8933" order="1">Schulte T</author>
                    <author authorORCID="0000-0002-7219-3097" order="2">Speranzini V</author>
                    <author authorORCID="0000-0003-3287-9024" order="3">Chaves-Sanjuan A</author>
                    <author authorORCID="0009-0000-7726-8580" order="4">Milazzo M</author>
                    <author authorORCID="0000-0001-6678-5873" order="5">Ricagno S</author>
                    <title>Helical superstructures between amyloid and collagen VI in heart-derived fibrils from a patient with Light Chain Amyloidosis</title>
                    <journal></journal>
                    <journalAbbreviation></journalAbbreviation>
                    <country></country>
                    <details>Particle stacks of the initial and the final set of segments used in the deposited reconstructions. 
The initial set of segments extracted from raw micrographs are the in the /initial_particles folder. Inside there is an initial_particle.star and the associated /particles folder.
The segments used in the final reconstructions EMD-50270, EMD-50271 and EMD-50272 are deposited in the  /straight_particles /bent_particles /mixed_particles folders, respectively. Each contain a *.star file and the associated particles folder.</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Initial set of segments of the AL59 reconstructions</name>
        <directory>/data/initial_particles</directory>
        <category>picked particles - single frame - processed</category>
        <headerFormat>MRCS</headerFormat>
        <dataFormat>MRCS</dataFormat>
        <numImagesOrTiltSeries>240985</numImagesOrTiltSeries>
        <framesPerImage>1</framesPerImage>
        <voxelType>UNSIGNED 32 BIT INTEGER</voxelType>
        <dimensions>
            <imageWidth>340</imageWidth>
            <pixelWidth>0.889</pixelWidth>
            <imageHeight>340</imageHeight>
            <pixelHeight>0.889</pixelHeight>
        </dimensions>
        <details></details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
    <imageSet>
        <name>Set of segments of the AL59 'straight' polymorph reconstruction (EMD-50270)</name>
        <directory>/data/straight_particles</directory>
        <category>picked particles - single frame - unprocessed</category>
        <headerFormat>MRCS</headerFormat>
        <dataFormat>MRCS</dataFormat>
        <numImagesOrTiltSeries>37904</numImagesOrTiltSeries>
        <framesPerImage>1</framesPerImage>
        <voxelType>UNSIGNED 16 BIT INTEGER</voxelType>
        <dimensions>
            <imageWidth>340</imageWidth>
            <pixelWidth>0.889</pixelWidth>
            <imageHeight>340</imageHeight>
            <pixelHeight>0.889</pixelHeight>
        </dimensions>
        <details></details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
    <imageSet>
        <name>Set of segments of the AL59 'bent' polymorph reconstruction (EMD-50271)</name>
        <directory>/data/bent_particles</directory>
        <category>picked particles - single frame - unprocessed</category>
        <headerFormat>MRCS</headerFormat>
        <dataFormat>MRCS</dataFormat>
        <numImagesOrTiltSeries>10521</numImagesOrTiltSeries>
        <framesPerImage>1</framesPerImage>
        <voxelType>UNSIGNED 16 BIT INTEGER</voxelType>
        <dimensions>
            <imageWidth>340</imageWidth>
            <pixelWidth>0.889</pixelWidth>
            <imageHeight>340</imageHeight>
            <pixelHeight>0.889</pixelHeight>
        </dimensions>
        <details></details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
    <imageSet>
        <name>Set of segments of the AL59 'mixed' polymorph reconstruction (EMD-50272)</name>
        <directory>/data/mixed_particles</directory>
        <category>picked particles - single frame - unprocessed</category>
        <headerFormat>MRCS</headerFormat>
        <dataFormat>MRCS</dataFormat>
        <numImagesOrTiltSeries>12355</numImagesOrTiltSeries>
        <framesPerImage>1</framesPerImage>
        <voxelType>UNSIGNED 16 BIT INTEGER</voxelType>
        <dimensions>
            <imageWidth>340</imageWidth>
            <pixelWidth>0.889</pixelWidth>
            <imageHeight>340</imageHeight>
            <pixelHeight>0.889</pixelHeight>
        </dimensions>
        <details></details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
