REL 2026-02-19 2026-10-06 2026-10-06 tolvaptan-bound V2R-BRIL with and without Fab 0000-0002-1941-5535 Hideaki E Kato Research Center for Advanced Science and Technology, The University of Tokyo 4-6-1 Komaba Meguro Tokyo Japan 153-8904 0000-0002-1941-5535 Hideaki E Kato Research Center for Advanced Science and Technology, The University of Tokyo 4-6-1 Komaba Meguro Tokyo Japan 153-8904 Kojima A Kawakami K Kobayashi K Matsui TE Fukuda M Kato HE 5.5 10.6019/EMPIAR-13413 EMDB molecule EMD-64538 EMD-64539 Kawakami K Kobayashi N Kobayashi K Matsui TE Uemoto K Gu Y Narita TJ Kugawa M Fukuda M Kato HE Kojima A A Rapid and Universal Pipeline for High-Resolution GPCR Structure Determination through <i>In Silico</i> Construct Optimization and de novo Protein Design bioRxiv 2026 10.64898/2026.04.02.716066 tolvaptan-bound V2R-BRIL with Fab :: imageset_1 /data/tolvaptan_bound_V2R_BRIL_with_Fab/data1 micrographs - multiframe TIFF TIFF 7002 48 1 48 UNSIGNED BYTE 5760 0.83 4092 0.83
- Please ignore the pixel size in the header (1.00 Å/px); use 0.83 Å/px. - Accelerating voltage: 300 kV - Spherical aberration: 2.7 mm - Total exposure dose: 50.0 e/A^2
 tolvaptan-bound V2R-BRIL with Fab :: imageset_2 /data/tolvaptan_bound_V2R_BRIL_with_Fab/data2 micrographs - multiframe TIFF TIFF 8046 48 1 48 UNSIGNED BYTE 5760 0.83 4092 0.83
- Please ignore the pixel size in the header (1.00 Å/px); use 0.83 Å/px. - Accelerating voltage: 300 kV - Spherical aberration: 2.7 mm - Total exposure dose: 50.0 e/A^2
 tolvaptan-bound V2R-BRIL without Fab /data/tolvaptan_bound_V2R_BRIL_without_Fab/20221112 micrographs - multiframe TIFF TIFF 11178 48 1 48 UNSIGNED BYTE 5760 0.83 4092 0.83
- Please ignore the pixel size in the header (1.00 Å/px); use 0.83 Å/px. - Accelerating voltage: 300 kV - Spherical aberration: 2.7 mm - Total exposure dose: 47.1 e/A^2