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        <keyDates>
            <depositionDate>2025-12-22</depositionDate>
            <releaseDate>2026-08-07</releaseDate>
            <updateDate>2026-08-07</updateDate>
        </keyDates>
        <title>Bovine lactoferrin particles in TBS for energy landscape analysis.</title>
        <correspondingAuthor private="true">
            <authorORCID>0009-0002-8934-9972</authorORCID>
            <firstName>Mutsuyo</firstName>
            <lastName>Wada</lastName>
            <organization type="academic">Domain Specific AI Core Project, Artificial Intelligence Laboratory, Fujitsu Research, Fujitsu Ltd.</organization>
            <street>1-1, Kamikodanaka 4-chome, Nakahara-ku</street>
            <townOrCity>Kawasaki</townOrCity>
            <stateOrProvince>Kanagawa</stateOrProvince>
            <country>Japan</country>
            <postOrZipCode>211-8588</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0009-0002-8934-9972</authorORCID>
            <firstName>Mutsuyo</firstName>
            <lastName>Wada</lastName>
            <organization type="academic">Domain Specific AI Core Project, Artificial Intelligence Laboratory, Fujitsu Research, Fujitsu Ltd.</organization>
            <street>1-1, Kamikodanaka 4-chome, Nakahara-ku</street>
            <townOrCity>Kawasaki</townOrCity>
            <stateOrProvince>Kanagawa</stateOrProvince>
            <country>Japan</country>
            <postOrZipCode>211-8588</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0009-0002-8934-9972">Wada M</author>
            <author authorORCID="0000-0003-4827-9488">Yamazaki K</author>
            <author authorORCID="0000-0002-5214-1265">Wada Y</author>
            <author>Ohga K</author>
            <author>Ishii Y</author>
            <author authorORCID="0009-0008-1563-1573">Nakagawa A</author>
            <author>Yoshikawa H</author>
            <author>Okuno S</author>
            <author>Nojima T</author>
            <author>Ochi H</author>
            <author>Hirose M</author>
            <author>Kato T</author>
            <author authorORCID="0009-0003-3849-7649">Katoh T</author>
        </authorsList>
        <grantSupport>
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                <fundingBody></fundingBody>
                <code></code>
                <country></country>
            </grantReference>
        </grantSupport>
        <datasetSize units="TB">2.4</datasetSize>
        <entryDOI>10.6019/EMPIAR-13708</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
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    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-68586</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0009-0002-8934-9972" order="1">Wada M</author>
                    <author authorORCID="0000-0003-4827-9488" order="2">Yamazaki K</author>
                    <author authorORCID="0000-0002-5214-1265" order="3">Wada Y</author>
                    <author order="4">Ohga K</author>
                    <author order="5">Ishii Y</author>
                    <author authorORCID="0009-0008-1563-1573" order="6">Nakagawa A</author>
                    <author order="7">Yoshikawa H</author>
                    <author order="8">Okuno S</author>
                    <author order="9">Nojima T</author>
                    <author order="10">Ochi H</author>
                    <author order="11">Hirose M</author>
                    <author order="12">Kato T</author>
                    <author authorORCID="0009-0003-3849-7649" order="13">Katoh T</author>
                    <title>Generation of Conformational Energy Landscape from Lactoferrin cryo-EM images with Mitigated Preferred Orientations by cryoTWIN</title>
                    <journal>SPIE</journal>
                    <journalAbbreviation></journalAbbreviation>
                    <country>United States</country>
                    <volume>14267</volume>
                    <year>2026</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1117/12.3119418</externalReferences>
                    <details>207,332 particles in MRC format</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>imageset_1</name>
        <directory>/data/movies</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>8443</numImagesOrTiltSeries>
        <framesPerImage>64</framesPerImage>
        <frameRange>
            <frameRangeMin>1</frameRangeMin>
            <frameRangeMax>64</frameRangeMax>
        </frameRange>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>4092</imageWidth>
            <pixelWidth>0.675</pixelWidth>
            <imageHeight>5760</imageHeight>
            <pixelHeight>0.675</pixelHeight>
        </dimensions>
        <details>- Microscope: FEI TITAN Krios
- Detector: Gatan K3 BIOQUANTUM
- Acceleration voltage (kV): 300
- Spherical aberration (Cs) : 2.7
- Nominal Defocus (μm): 0.8 - 2.0
- Average electron dose per image (e-/A2): 50.2
- Please use 'CountCDSRef_250304_slot2_43-107_19.51.11_X+0Y-1-0.mrc' as a gain reference without rotation and y-flipping.</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
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