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        <title>SpCas9 bound to 14 nucleotide complementary DNA substrate</title>
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            <authorORCID>0000-0002-7601-210X</authorORCID>
            <firstName>Martin</firstName>
            <lastName>Jinek</lastName>
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            <author authorORCID="0000-0003-1560-5769">Pacesa M</author>
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            <author authorORCID="0000-0003-3558-7211">Muckenfuss LM</author>
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            <author authorORCID="0000-0002-7601-210X">Jinek M</author>
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                    <author authorORCID="0000-0003-1560-5769" order="1">Pacesa M</author>
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                    <author authorORCID="0000-0002-7601-210X" order="6">Jinek M</author>
                    <title>R-loop formation and conformational activation mechanisms of Cas9</title>
                    <journal>Nature</journal>
                    <journalAbbreviation>Nature</journalAbbreviation>
                    <country></country>
                    <issue>7925</issue>
                    <volume>609</volume>
                    <firstPage>191</firstPage>
                    <lastPage>196</lastPage>
                    <year>2022</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1038/s41586-022-05114-0</externalReferences>
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        <details>Unaligned multi-frame movies with each containing 36 frames per movie collected at 300 kV in super-resolution counting mode. Total accumulated electron exposure on the specimen level corresponds to 66.8 electrons per Å^2. Movies are not gain corrected and the gain reference is provided. Data acquired with EPU.</details>
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